Fantastický Pedrosa porazil konkurenty s velkou převahou, 2. Dovizioso, až za ním Yamahy
Výsledky pátečního tréninku na VC San Marina v Misanu:
| P. | Jezdec | Tým | N° | Moto | Čas | Ztráta | Kola | km/h | |
| 1. |  |
Dani Pedrosa | Repsol Honda Team | 26 | Honda | 1:34,772 | 27 | 160,528 | |
| 2. |  |
Andrea Dovizioso | Repsol Honda Team | 4 | Honda | 1:35,384 | 0,612 | 27 | 159,498 |
| 3. | |
Jorge Lorenzo | Fiat Yamaha Team | 99 | Yamaha | 1:35,444 | 0,672 | 29 | 159,398 |
| 4. | |
Valentino Rossi | Fiat Yamaha Team | 46 | Yamaha | 1:35,539 | 0,767 | 30 | 159,239 |
| 5. |  |
Colin Edwards | Monster Yamaha Tech 3 | 5 | Yamaha | 1:35,834 | 1,062 | 28 | 158,749 |
| 6. | |
Ben Spies | Monster Yamaha Tech 3 | 11 | Yamaha | 1:35,892 | 1,120 | 30 | 158,653 |
| 7. | |
Nicky Hayden | Ducati Marlboro Team | 69 | Ducati | 1:36,028 | 1,256 | 26 | 158,428 |
| 8. |  |
Casey Stoner | Ducati Marlboro Team | 27 | Ducati | 1:36,072 | 1,300 | 19 | 158,356 |
| 9. | |
Marco Melandri | San Carlo Honda Gresini | 33 | Honda | 1:36,126 | 1,354 | 26 | 158,267 |
| 10. | |
Loris Capirossi | Rizla Suzuki MotoGP | 65 | Suzuki | 1:36,277 | 1,505 | 29 | 158,019 |
| 11. | |
Héctor Barbera | Paginas Amarillas Aspar | 40 | Ducati | 1:36,293 | 1,521 | 29 | 157,992 |
| 12. |  |
Randy de Puniet | LCR Honda MotoGP | 14 | Honda | 1:36,454 | 1,682 | 26 | 157,729 |
| 13. | |
Marco Simoncelli | San Carlo Honda Gresini | 58 | Honda | 1:36,533 | 1,761 | 27 | 157,599 |
| 14. | |
Aleix Espargaro | Pramac Racing Team | 41 | Ducati | 1:36,716 | 1,944 | 27 | 157,301 |
| 15. |  |
Hiroshi Aoyama | Interwetten-Honda MotoGP | 7 | Honda | 1:37,001 | 2,229 | 26 | 156,839 |
| 16. |  |
Mika Kallio | Pramac Racing Team | 36 | Ducati | 1:37,697 | 2,925 | 27 | 155,722 |
| 17. | |
Álvaro Bautista | Rizla Suzuki MotoGP | 19 | Suzuki | 1:37,900 | 3,128 | 27 | 155,399 |
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