2. trénink: Lorenzo nejrychlejší, 2. Pedrosa, skvělé představení veterána Edwardse
Výsledky 2. měřeného tréninku v Misanu:
| P. | Jezdec | Tým | N° | Moto | Čas | Ztráta | Kola | km/h | |
| 1. |  |
Jorge Lorenzo | Fiat Yamaha Team | 99 | Yamaha | 1:34,627 | 28 | 160,774 | |
| 2. | |
Dani Pedrosa | Repsol Honda Team | 26 | Honda | 1:34,731 | 0,104 | 30 | 160,597 |
| 3. |  |
Casey Stoner | Ducati Marlboro Team | 27 | Ducati | 1:34,763 | 0,136 | 22 | 160,543 |
| 4. |  |
Colin Edwards | Monster Yamaha Tech 3 | 5 | Yamaha | 1:34,774 | 0,147 | 29 | 160,525 |
| 5. |  |
Valentino Rossi | Fiat Yamaha Team | 46 | Yamaha | 1:34,981 | 0,354 | 29 | 160,175 |
| 6. | |
Andrea Dovizioso | Repsol Honda Team | 4 | Honda | 1:35,053 | 0,426 | 29 | 160,053 |
| 7. | |
Nicky Hayden | Ducati Marlboro Team | 69 | Ducati | 1:35,069 | 0,442 | 26 | 160,026 |
| 8. | |
Héctor Barbera | Paginas Amarillas Aspar | 40 | Ducati | 1:35,120 | 0,493 | 23 | 159,941 |
| 9. | |
Ben Spies | Monster Yamaha Tech 3 | 11 | Yamaha | 1:35,217 | 0,590 | 28 | 159,778 |
| 10. | |
Loris Capirossi | Rizla Suzuki MotoGP | 65 | Suzuki | 1:35,222 | 0,595 | 29 | 159,769 |
| 11. | |
Álvaro Bautista | Rizla Suzuki MotoGP | 19 | Suzuki | 1:35,432 | 0,805 | 28 | 159,418 |
| 12. | |
Marco Melandri | San Carlo Honda Gresini | 33 | Honda | 1:35,445 | 0,818 | 27 | 159,396 |
| 13. |  |
Randy de Puniet | LCR Honda MotoGP | 14 | Honda | 1:35,636 | 1,009 | 28 | 159,078 |
| 14. | |
Aleix Espargaro | Pramac Racing Team | 41 | Ducati | 1:35,790 | 1,163 | 25 | 158,822 |
| 15. | |
Marco Simoncelli | San Carlo Honda Gresini | 58 | Honda | 1:36,040 | 1,413 | 27 | 158,408 |
| 16. |  |
Hiroshi Aoyama | Interwetten-Honda MotoGP | 7 | Honda | 1:36,089 | 1,462 | 28 | 158,328 |
| 17. |  |
Mika Kallio | Pramac Racing Team | 36 | Ducati | 1:36,207 | 1,580 | 26 | 158,134 |
Kvalifikace MotoGP začíná v 13:55.
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